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Potential for Cripto-1 as a Biomarker for Cancer and Therapeutic Target. A) Cripto-1 is expressed in breast cancer tissue and in plasma samples from breast cancer patients. B) Effect of anti-Cripto-1 monoclonal blocking antibody on growth of NCCIT human teratocarcinoma cells in vivo. Anti-Cripto-1 blocking antibody negatively affects growth of NCCIT in a xenograft model.
