Table 3. Final ATRIA Risk Score: Model Regression Coefficients and Hazard Ratios from Derivation, Validation, and Combined Cohorts.
| Derivation Cohort | Validation Cohort | Combined Cohort | |||||
|---|---|---|---|---|---|---|---|
| Variable | Points | Regression Coefficient | Hazard Ratio | Regression Coefficient | Hazard Ratio | Regression Coefficient | Hazard Ratio |
| Anemia | 3 | 1.19 | 3.28 | 1.17 | 3.22 | 1.18 | 3.27 |
| Severe renal disease* | 3 | 0.97 | 2.63 | 0.88 | 2.40 | 0.93 | 2.53 |
| Age ≥ 75 years | 2 | 0.71 | 2.03 | 0.65 | 1.92 | 0.69 | 1.99 |
| Any prior hemorrhage diagnosis | 1 | 0.52 | 1.68 | 0.28 | 1.32 | 0.44 | 1.56 |
| Diagnosed hypertension | 1 | 0.27 | 1.31 | 0.43 | 1.54 | 0.32 | 1.38 |
*
Defined as eGFR < 30 mL/min or dialysis-dependent