Table 2.

Patient and transplant center characteristics associated with DRI of liver transplants

		Coefficient	P value
Patient characteristics	Age, per decade	.02	<0.001
	Encephalopathy (mild, moderate, severe)	.02	<0.001
	Male gender	−.06	<0.001
	MELD, per ten points	−.05	<0.001
	Priority exception (yes/no)	−.04	<0.001
	Prior liver transplant (yes/no)	−.09	<0.001
	Hepatitis C (yes/no)	−.03	<0.001
	Ascites (mild, moderate, severe)	−.01	0.07
Transplant center characteristics	Liver transplants performed per year, per ten transplants	.006	<0.001
	Mean MELD at transplant/10 points	.01	0.5
	Multiple centers within OPO (competition)	.05	0.013
	Proportion of transplants with MELD exceptions	−0.04	0.57

DRI = Donor Risk Index. MELD = Model for End-stage Liver Disease, OPO = Organ Procurement Organization. Based upon multivariable mixed-effects hierarchical regression which adjusts for clustering at the center, OPO, and Region levels. Statistically significant results are in bold. For the purpose of reference, a difference of 0.1 in DRI is associated with an approximately 2% difference in risk of graft failure at 3 years after transplant(3).