Table 2.
Associations between psoriasis and risk of total cancer and cancers of breast, lung, and colon, IWHS/Medicare, 1991–2006
| Incident cancer | Psoriasis | Number of cancers | Person-years | Incidence rate per 1,000, age-adjusted |
HR, age-adjusted (95% CI) |
HR, multivariate- adjusteda (95% CI) |
|---|---|---|---|---|---|---|
| Total | No | 6,381 | 384,037 | 16.5 | 1 | 1 |
| Yes | 107 | 5,141 | 20.8 | 1.2 (1.0–1.4) | 1.1 (0.9–1.4) | |
| Breastb | No | 2,037 | 402,199 | 5.1 | 1 | 1 |
| Yes | 29 | 5,477 | 5.3 | 1.0 (0.7–1.5) | 1.0 (0.7–1.5) | |
| Lung | No | 722 | 414,074 | 1.7 | 1 | 1 |
| Yes | 20 | 5,703 | 3.5 | 1.9 (1.2–3.0) | 1.3 (0.8–2.0) | |
| Colon | No | 925 | 411,031 | 2.2 | 1 | 1 |
| Yes | 22 | 5,637 | 3.9 | 1.6 (1.1–2.5) | 1.6 (1.0–2.4) |
a
Adjusted for age at the start of follow-up, BMI, education, smoking status, pack-years, physical activity, and history of HT use
b
Additionally adjusted for number of live births