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. Author manuscript; available in PMC: 2012 Sep 1.
Published in final edited form as: Cancer Epidemiol Biomarkers Prev. 2011 Jul 8;20(9):1861–1864. doi: 10.1158/1055-9965.EPI-11-0360

Table 2.

Hazard ratios (HR) of colorectal cancer (CRC), colon cancer, and rectal cancer in relation to eosinophil count at baseline in ARIC, 1987–2006

Eosinophil count, cells/mcl Number of CRC Person-years Hazard ratio (95%CI)
CRC Model 1a CRC Model 2b Colon cancer Model 2b Rectal cancer Model 2b
≤70 96 59,004 1.0 1.0 1.0 1.0
70–176 84 59,310 0.81 (0.59;1.12) 0.70 (0.50;0.98) 0.74 (0.51;1.07) 0.54 (0.25;1.17)
≥177 62 56,685 0.64 (0.46;0.91) 0.58 (0.40;0.83) 0.49 (0.32;0.75) 0.90 (0.45;1.79)
P-trend 0.01 0.003 0.001 0.85
a

Model 1-adjusted for age, race, sex, and ARIC center

b

Model 2 -- Model 1, additionally adjusted for education, BMI, smoking status and pack-years of smoking, alcohol, diabetes, WBC count and fibrinogen.