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Heat map of various genes expressed by differentiated retinal neurons and the pineal gland. Log2 expression levels are shown in a green-black-red gradient. Genes expressed by photoreceptors (A), ganglion cells (B), amacrine cells (C), and horizontal cells (E) are present by 9 weeks, whereas those in the pineal gland (D) are absent in our cultures. Mature markers of photoreceptors such as opsins are poorly expressed by 9 weeks in culture or by 96 days in vivo.
