Figure 7.

NOD2 deficiency results in skewed cytokine responses to PGN. NOD2 KO or WT controls were administered an i.v.t. injection of 5 μg PGN or saline, and cytokine production in eye tissue homogenates was assessed by ELISA 6 hours later. Values are mean ± SE (n = 5–7 mice per group). *P < 0.05 saline vs. PGN within a genotype; ψP < 0.05 KO vs. WT mice treated with PGN.