Figure 1.

Corneal inflammatory lymphangiogenesis is inhibited by VLA-1 blockade. (A) Representative images of immunofluorescence microscopic assays showing significantly reduced lymphatic vessels in the inflamed corneas after VLA-1 antibody treatment. Red: LYVE-1. Dotted lines: Limbus. Scale bars, 200 μm. (B, C) Summarized data showing the difference on newly formed lymphatic vessels between the VLA-1 antibody and isotype control treatment groups in terms of vessel clockwise extent (B) and coverage area (C). *P < 0.05.