Figure 5.

Analysis of the ERG function in eyes of Mertk^nmf12 mutants. Although dying cells are present throughout the retinas of Mertk^nmf12 homozygotes, the majority of photoreceptor cells in the central portion of the retina of Mertk^nmf12 homozygotes are preserved. This preservation is reflected in the ERG waveforms. Although the amplitude of the waveforms recorded from homozygous Mertk^nmf12 retina are progressively reduced over time compared with those of C57BL/6J mice, ERG waveforms are still detectable from eyes of Mertk^nmf12 homozygotes aged up to 2 years.