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Photopic spatial frequency threshold estimated through the optomotor reflex in mouse strains, based on B6 and D2 genetic backgrounds. D2-Gpnmb+ and D2 mice, never elicited a response; thus, acuity was 0. The B6-based B6.isaD2ipdD2 strain carried the D2 versions of isa and ipd regions. B6D2F1 mice are the first generation of a B6 and D2 cross. n, the number of older than 1 month old mice tested, ***P < 0.001.
