Skip to main content
. 2011 Aug 11;52(9):6384–6395. doi: 10.1167/iovs.11-7666

Figure 7.

Figure 7.

Blocking VEGF inhibits NV and revascularization in OIR but does not prevent the disruption of the astrocyte network. OIR mice were intravitreally injected with PBS (Veh) or VEGF blocker (VEGFR1/Fc, 2 μg/eye) at P14. Retinal vasculature (isolectin B4, red) and astrocyte network (GFAP, green) were analyzed at P17 in flatmount. (A) Representative images of retinal flatmount and quantification of NV and avascular areas (n = 4 retinas from 4 mice). *P < 0.05 compared with Veh. Original magnification, ×5. (B) Representative confocal images of astrocyte in the central retina are shown (n = 4 retinas from 4 mice). Original magnification, ×20.