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. 2011 Aug 11;52(9):6384–6395. doi: 10.1167/iovs.11-7666

Figure 8.

Figure 8.

VEGF supplement does not induce NV in hyperoxia-treated OIR mice. OIR mice were intravitreally injected with PBS (Veh) or VEGF (2 μg/eye) at P14 and then were treated with hyperoxia (75% oxygen) from P14 to P17. (A) VEGF levels in the ocular of P17 mice were determined by ELISA and normalized to vehicle control (n = 3 eyes from 3 mice). (B) Retinal vasculature (isolectin B4, red) at P17 in flatmount and quantification of NV and avascular areas were shown (n = 6 retinas from 6 mice). Original magnification, ×5.