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. 2011 Aug 22;52(9):6604–6616. doi: 10.1167/iovs.11-7375

Table 5.

Effect of TFB-TBOA and MSO Combined on Retinal Features

Condition (n) NFLT vs. RT (%) [P] GC Count (n) [P] NDS (n) [P]
10 mm Hg (6) 1.8 ± 0.6 [–] 0.1 ± 0.1 [–] 0.2 ± 0.1 [–]
20 nM TBOA + 1 mM MSO (7) 12.5 ± 4.4 [<0.0001]* 18.1 ± 4.7 [<0.0001]* 3.0 ± 1.1 [<0.0001]*
20 nM TBOA + 2 mM MSO (6) 14.2 ± 1.6 [<0.0001]* 22.5 ± 2.7 [<0.0001]* 3.2 ± 0.4 [<0.0001]*
40 nM TBOA + 1 mM MSO (5) 13.2 ± 0.7 [<0.0001]* 24.1 ± 4.1 [<0.0001]* 3.7 ± 0.5 [<0.0001]*
40 nM TBOA + 2 mM MSO (6) 12.2 ± 0.6 [<0.0001]* 26.5 ± 2.3 [<0.0001]* 3.8 ± 0.4 [<0.0001]*

Data are the mean ± SD. The density of damaged ganglion cells was counted per 100 μm of the retina. P values were calculated versus control (10 mm Hg) by Student's t-test.

*

Statistically significant at P < 0.05.

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