Table 2.
Response Parameter of Single-Cell Recordings
| WT | Grk1+/− | Grk1+ | Grk1+b | |
|---|---|---|---|---|
| Dark current, pA | 14.9 ± 0.6 (36) | 13.7 ± 0.9 (16) | 13.8 ± 0.6 (21) | 14.9 ± 0.6 (24) |
| Sensitivity Io, photons μm−2 | 27.5 ± 2.0 (36)* | 17.0 ± 1.2 (15)† | 27.3 ± 2.0 (21)* | 31.4 ± 2.8 (24)‡ |
| Time to peak, ms | 176 ± 4 (36) | 187 ± 5 (15) | 180 ± 6 (21) | 175 ± 3 (24) |
| Integration time, ms | 356 ± 21 (36)‡ | 570 ± 50 (15)§ | 254 ± 15 (21)‡§ | 338 ± 22 (24)‡ |
| Recovery time constant, τrec, ms | 223 ± 9 (36)‡ | 343 ± 38 (15)§ | 182 ± 16 (21)†‡ | 211 ± 16 (24)‡ |
| Dominant time constant of recovery, τD, ms | 271 ± 13 (26) | 271 ± 28 (11) | 274 ± 17 (14) | 251 ± 11 (16) |
Values given as mean ± SEM (n). Recovery time constant (τrec) was determined by fitting a single exponential function to the second half of the shut off of the dim flash response. Dominant recovery time constant of recovery (τD) was determined by the slope of Pepperberg plot. Statistical analysis was carried out by one-way ANOVA with the post hoc Tukey Honestly Significant Difference test.
*
Significantly different from Grk1+/− at 5% level.
†
Significantly different from WT at 5% level.
‡
Significantly different from Grk1+/− at 1% level.
§
Significantly different from WT at 1% level.