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. 2011 Jul 15;52(8):5189–5201. doi: 10.1167/iovs.11-7470

Figure 9.

Figure 9.

Mislocalization of opsins and upregulation of GFAP in mRDef transgenic mice. (A) Immunohistochemical analysis of opsin localization in retinal cryosections with a green cone opsin–specific antibody. (Left) Wild-type, (middle) mRDefRpgr−/− transgenic, and (right) mROrfRpgr−/− transgenic retina. (B) Upregulation of GFAP immunoreactivity in mRDefRpgr−/− retina. (Left) Wild-type, (middle) mRDefRpgr−/− transgenic, and (right) mROrfRpgr−/− transgenic retina. RPE, retinal pigment epithelium; ONL, outer nuclear layer; INL, inner nuclear layer; GC, ganglion cell layer.