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Versican and ADAMTS4 mRNA levels in densely and sparsely Qdot-labeled regions. Versican mRNA levels inversely correlated with Qdot labeling patterns; there was high versican mRNA levels in regions of sparse labeling and low levels in densely labeled regions. ADAMTS4, an enzyme that cleaves versican, showed no significant regional distribution. Data were normalized for GAPDH. Error bars represent the SEM, where n = 6, P = 0.02 for versican between high- and low-flow areas.
