Figure 7 .

EFL-3 and LIN-39 interact to specify ventral nerve cord development. (A) LIN-39 provides spatial-specific information to developing lineages. EFL-3 provides information within each lineage to specify cell fate between the different cell types. (B) In the midbody P3–P8 lineages, EFL-3 and LIN-39 integrate their lineage and spatial-specific cues on the egl-1 promoter. EFL-3 and LIN-39 co-repress egl-1 in the VA and VB neurons, with LIN-39 functioning as a weaker repressor. In the VC neurons, LIN-39 is necessary to repress egl-1. EFL-3 is not expressed in the VC neurons and has no apparent affect on egl-1 expression in the VCs. Green dots represent neurons that express lin-39; orange dots represent neurons that express efl-3.