Table 3. Top 15 downregulated genes obtained in the microarray hybridization experiments.
Top | Locus | Gene description | Log2 ratio light vs. dark | Fold change | SD |
---|---|---|---|---|---|
1 | AN1052 | velvetA(veA) | −3.11 | 8.60 | 0.242 |
2 | AN8647 | ALS family protein | −2.65 | 6.28 | 0.722 |
3 | AN1008 | Putative nitrate transporter (crnA) | −2.37 | 5.17 | 0.228 |
4 | AN5558 | Alkaline protease (prtA) | −2.31 | 4.95 | 0.255 |
5 | AN3304 | GABA transporter, putative | −2.20 | 4.59 | 0.611 |
6 | AN0231 | Conidiophore-specific phenol oxidase (ivoB) | −2.14 | 4.40 | 0.074 |
7 | AN8063 | Acid phosphatase activity | −1.98 | 3.94 | 0.094 |
8 | AN9076 | Putative adhesin function | −1.97 | 3.91 | 0.751 |
9 | AN2926 | 60S ribosomal protein Nsa2, putative | −1.95 | 3.86 | 0.183 |
10 | AN8539 | GNAT family acetyltransferase, putative | −1.92 | 3.78 | 0.309 |
11 | AN5353 | Hypothetical protein | −1.89 | 3.70 | 0.381 |
12 | AN9240 | Putative C2H2 finger domain transcription factor | −1.81 | 3.49 | 0.829 |
13 | AN0367 | Integral membrane protein | −1.80 | 3.49 | 0.310 |
14 | AN0190 | Subunit of the tRNA splicing endonuclease, | −1.77 | 3.41 | 0.117 |
15 | AN1131 | Cytosolic Cu/Zn superoxide dismutase, putative | −1.75 | 3.36 | 0.763 |
Average of log2 of the ratio of light vs. dark was used to calculate the fold change. SD is the standard deviations of log2 of ratio of a swap-dye experiment. The gene descriptions were determined using the Aspergillus genome database AspGD (www.aspergillusgenome.org). Hypothetical proteins have unknown function but are conserved proteins.