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. 2011 Sep;189(1):11–21. doi: 10.1534/genetics.111.130781

Figure 7 .

Figure 7 

Altered H4K16Ac affects chromosome segregation. Chromosome loss assays were done with wild-type strains carrying a nonessential minichromosome (YPH1015) with vector or SAS2, SAS4, or SAS5 expressed under the GAL1 promoter. Loss of the minichromosome within the first cell division gives rise to colonies that are half red and half white. We measured colonies that were at least half red. (A) Bar graph showing the number of half-sectored colonies per 1000 for each strain on galactose media without (Gal) or with NAM (Gal + 30 mM NAM). (B) Bar graph shows the number of half-sectored colonies per 1000 for SIR2 deletion strain (YMB7911) carrying pRS314 (vector), sir2-H364Y (catalytic mutant), or SIR2. Error bars show standard error of the mean from three biological replicates.