Figure 8 .

An H4K16Q acetylmimic mutant shows increased chromosome loss. Chromosome loss assays were performed with strains carrying a nonessential minichromosome that expresses wild-type H4 (YMB8155), H4K16R (YMB8156), or H4K16Q (YMB8157). Loss of the minichromosome within the first cell division gives rise to colonies that are half red and half white. We measured colonies that were at least half red. Bar graph shows the number of half-sectored colonies per 1000. Shown are results for three independent experiments and error bars show standard error of the mean.