Table 3.
Number and proportions of patients who used two or more antihypertensive drugs concurrently and adjusted odds ratios for change
| Intervention | Controls | Intergroup comparison | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| 2001 | 2003 | Adjusted* OR (95% CI) | p-value | 2001 | 2003 | Adjusted* OR (95% CI) | p-value | Adjusted* OR (95% CI) | p-value | |
| n (%) | n (%) | |||||||||
| Hypertension | ||||||||||
| 828 (36.8) | 1164 (39.2) | 1.12 (0.99, 1.25) | 0.06 | 2119 (38.5) | 2774 (41.3) | 1.13 (1.05, 1.21) | 0.002 | 0.99 (0.86, 1.13) | 0.86 | |
| CHD | ||||||||||
| 110 (34.4) | 164 (37.3) | 1.19 (0.87, 1.62) | 0.23 | 292 (30.7) | 389 (33.9) | 1.10 (0.91, 1.33) | 0.33 | 1.07 (0.75, 1.54) | 0.70 | |
| Diabetes | ||||||||||
| 144 (47.7) | 250 (54.8) | 1.33 (0.99, 1.79) | 0.06 | 303 (49.5) | 428 (51.7) | 1.10 (0.89, 1.36) | 0.38 | 1.22 (0.85, 1.75) | 0.28 | |
Prescription data was drawn from the national Prescription Register during a three-month period in 2001 and 2003.
Abbreviations: CHD, coronary heart disease; OR, Odds ratio; CI, confidence interval.
*Within-group analysis: Logistic regression, random effects model (physician as a random effect). Adjusted for patient's age and patient's sex. Reference group: patients with one antihypertensive drug.
**Intergroup analysis: Logistic regression, random effects model (physician as a random effect). A product term between time (after versus before) and group (intervention versus control) was added in the model. Adjusted for patient's age and patient's sex. Reference group: patients with one antihypertensive drug.