Figure 5.

Dose response and growth curves of selected microtubule-interfering drugs. Leukemia cell lines were incubated with vinorelbine (A and B) or ixabepilone (C and D). (A and C) Cells were incubated with varying concentrations of drugs and assessed after 96 hours for survival compared with DMSO-treated cells. (B and D) Cells were incubated with 1 μM of drug and assessed every 24 hours for cell survival compared with DMSO-treated cells.

Notes: Data points and error bars are means and standard errors, respectively, of triplicate wells. A and C are representative of three separate experiments.

Abbreviation: DMSO, dimethylsulfoxide.