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. 2011 Sep 5;4:149–168. doi: 10.2147/OTT.S21553

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© 2011 Hoeksema et al, publisher and licensee Dove Medical Press Ltd.

This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited.

PMC Copyright notice

Relative effectiveness of selected drugs from the Approved Oncology Drug Set II on normal and patient samples. Heat map of drug effectiveness compared with MTX or AraC. Values are a ratio of the IC₅₀ of MTX or AraC to the IC₅₀ of each drug. Green, black, and red represent superior, equivalent, and inferior activity, respectively, to MTX or AraC. 17577, 87781, and 41304 represent the patient samples.

Abbreviations: AraC, cytarabine; BMS, bone marrow stroma; IC₅₀, half maximal inhibitory concentration; MTX, methotrexate; NHL, normal human lymphocytes.