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. 2011 Sep 19;6(9):e23558. doi: 10.1371/journal.pone.0023558

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Jin et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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(A) Representative light micrographs of common carotid arteries from Veh-, sense-OPN, and antisense-OPN treated rats at day 28 after balloon injury. Arterial sections were stained with HE stain. (B) Effects of administration of antisense-OPN on neointima area and neointima/media ratio of injured carotid arteries in rats at 28 days after carotid artery balloon injury. The results are taken from 3 rats per group and represent 3 independently performed experiments. Data are shown as mean+SEM. $ P<0.05 vs. Veh group and sense-OPN. * P<0.05 vs. normal arterial adventitial layers. # P<0.05 vs. arterial adventitial layers at day 28 after balloon injury.