Table 3.

Study Endpoints

Muscular morphology
• Mean fiber area
• Fiber type distribution
• Satellite cells
• Intracellular signaling molecules
Body Composition
• Lean Body Mass
• Fat percentage
Muscle strength
• Maximum Voluntary Contraction
• Leg Extensor Power
Systemic effects
• Cholesterol (TCHO, HDL, LDL, Triglycerides)
• Glucose
• Insulin
• Inflammatory markers (CRP, TNF-α, IL-6, IL-18)
• Anti-inflammatory markers (IL-4, IL-10)
Patient reported outcomes
• Health related Quality of Life (SF-36 and EORTC)