Table 2.
Gene | Haplotypes | n | % | Mutated codons |
---|---|---|---|---|
Pfdhfr (n = 61) |
CIRN | 31 | 51 | 3 |
CICN | 21 | 34 | 2 | |
CNRN | 4 | 6 | 2 | |
RICN | 4 | 6 | 3 | |
CIC N/S | 1 | 2 | 1 or 2 | |
Pfdhps (n = 30) |
SGKAA | 18 | 60 | 1 |
AGKAA | 7 | 23 | 2 | |
SAKAA | 2 | 7 | 0 | |
SGEAA | 1 | 3 | 2 | |
SGEGA | 2 | 7 | 3 |
Codon positions: pfdhfr C50R, N51I, C59R and S108N, pfdhps S436A/F/C, A437G, K540E, A581G and A613T/S. The sensitive haplotype is underlined and the mutated codons are shown in bold characters.