Table 1. Body weight, tissue mass and plasma IL-6 concentrations in wild-type and Apc^Min/+ mice grouped by percentage of body weight loss.

		Peak	Sac
		BW	BW	% Change	Gastroc	Epi Fat	Tibia Length	IL-6	Spleen
Group		(g)	(g)		(mg)	(mg)	(mm)	(pg/ml)	(mg)
Wt	n = 5	25.4±0.3	25.3±0.4	0.1±0.4	121.4±1.8	391±27	16.9±0.1	0±0	102±11
ApcMin/+
WS	n = 5	25.4±0.8	25.6±0.9	0.0±0.0	121.5±5.6	330±23	17.0±0.1	2.8±2	250±42*
≤5%	n = 6	23.4±0.2	22.5±0.2†	−4.1±0.6†	100.5±2.8†	122±26†	16.7±0.1	30±3†	425±13†
6–19%	n = 4	24.8±0.6	21.3±0.8†	−13.9±1.5†,&	82.3±3.8†,&	6.7±6.7†,&	17.1±0.1	108±36†,&	480±92†
≥20%	n = 6	25.2±0.5	19.8±0.3†	−21.4±0.6$	68.6±3.1$	0±0$	17.3±0.1	92±23†,&	379±41†

Wild-type mice at 16 weeks of age were used as non tumor bearing control. Values are means ± SE.

^†Signifies different from WS.

^&Signifies different from WS and <5% groups.

^$Signifies difference from all groups.

*Signifies different from wild-type mice.

WS, weight stable. Epi, Epididymal fat pad. Sac, sacrifice, BW, body weight, Wt, wild-type mice.