Table 4. Correlation between culture pH and chronological life span.

Strain (day)	Pearson coefficient (r)	p-value (T-test)
BY4743 (day 2)	0.92	<10−5
BY4743 (day 4)	0.89	<10−5
RM11 (day 2)	0.74	0.001
RM11 (day 4)	0.73	0.001

BY4743 and RM11 cells were aged in synthetic complete medium with different carbon sources as shown in Table 3 and Figure 5 . Culture pH was measured at either day 2 or day 4 of the experiment.