Figure 1.
ADSC secretion promotes MPG neurite growth.
Rat MPG dorsocaudal region was cultured in plain DMEM (A, Control Medium) or PSMC-conditioned DMEM (B), or in ADSC-conditioned DMEM (C) plus anti-CXCL5 antibody (D) or AG490 (E). For clarity, outgrowth of neurites was outlined by dashed lines. For quantification, the lengths of the 5 longest neurites in each of 18 specimens per treatment group were measured and their average shown on the Y-axis in Panel F. Alternatively quantification was done by measuring the neurite growth areas in each of 18 specimens per treatment group, the averages of which are shown on the Y-axis in Panel G.