Table 4.
Mean seasonally adjusted vitamin D levels stratified by rs2282679 (GC protein) genotype
Mean vitamin D level (SD) | TT | GT | GG |
---|---|---|---|
49.6 (21.4) | 43.7 (20.2) | 37.8 (16.8) | |
Weekend exposure in warmer months (h/day) | |||
≤3 | 44.7 (20.8) | 40.0 (19.5) | 34.7 (14.4) |
3–5 | 51.3 (20.8) | 45.6 (20.5) | 40.2 (18.7) |
>5 | 54.2 (22.4) | 48.1 (19.6) | 39.5 (18.7) |
Holiday exposure <45N (h) | |||
0 | 47.2 (21.1) | 37.9 (18.0) | 35.5 (14.8) |
0–87.5 | 49.8 (21.3) | 45.8 (20.0) | 41.5 (17.8) |
>87.5 | 52.8 (21.7) | 52.3 (20.8) | 36.7 (18.9) |
Supplementation | |||
No | 44.9 (20.1) | 38.9 (19.0) | 33.9 (14.5) |
Yes | 56.7 (20.3) | 52.4 (19.1) | 37.9 (16.4) |
Sensitivity | |||
Non-sun-sensitive | 50.8 (21.7) | 45.6 (20.4) | 41.7 (17.1) |
Sun-sensitive | 48.5 (21.2) | 41.9 (19.9) | 33.9 (15.8) |
Inheritance of less common variants in rs 2282679 (vitamin D-binding protein) is associated with lower levels of vitamin D. Here we show the effects of exposures moderating seasonally adjusted vitamin D level and the differences in levels achieved as a result of those exposures by genotype. The adjusted estimate assumes that blood was drawn in winter