Table 2.

MDSC, Treg and arginase I levels

Number patients median (range) P value	Control N = 54	Pancreas N = 46	Esophagus N = 60	Gastric N = 25	UGI cancer N = 125
MDSC (%)	N = 47	N = 44	N = 56	N = 23	N = 123
	0.8 (0.1, 2.0)	2.1 (0.2, 11.2)	1.3 (0.4, 6.0)	1.5 (0.2, 10.0)	1.4 (0.2, 11.2)
		P < 0.001	P < 0.001	P = 0.002	P < 0.001
Treg (%)	N = 46	N = 40	N = 51	N = 17	N = 108
	3.6 (0.6, 14.3)	7.5 (2.3, 20.6)	6.5 (1.0, 22.2)	7.8 (3.2, 20.2)	7.0 (1.0, 22.2)
		P < 0.001	P < 0.001	P = 0.002	P < 0.001
Arginase I conc. (ng/ml)	N = 31	N = 44	N = 53	N = 22	N = 119
	7.7 (5.0, 97.4)	16.7 (5.1, 293.0)	19.9 (5.1, 167.8)	36.5 (9.2, 195.0)	22.0 (5.1, 293.0)
		P = 0.020 (ns)	P < 0.001	P < 0.001	P < 0.001

Number of patients (N), median (range), Wilcoxon rank sum test P value of cancer group versus control. The UGI (upper gastrointestinal) cancer group consists of the pancreatic, esophageal and gastric cancer patients combined. Bonferonni correction applied due to multiple testing with the control arm, statistical significance adjusted to P < 0.0125