Table 2.

Heteroplasmic variants in different organs of the same individual (patient #11, 59 year old)

			Allele 1 frequency
Position	allele 1	allele 2	Cerebrum	Heart	Skeletal Muscle	Lung	Kidney	Spleen	Liver	Pancreas	Colon	Cerebellum	Number of tissues with variant	Min%	Max%
60	C	T*	<0.35%	<0.35%	<0.35%	<0.35%	2.16%	<0.35%	1.96%	<0.35%	<0.35%	<0.35%	2	<0.35%	2.16%
64	A	C*	<0.35%	<0.35%	1.73%	<0.35%	0.36%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	1	<0.35%	1.73%
72	C	T*	<0.35%	<0.35%	<0.35%	<0.35%	18.4%	<0.35%	11.7%	<0.35%	<0.35%	<0.35%	2	<0.35%	18.4%
73	G	A*	<0.35%	<0.35%	2.27%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	1	<0.35%	2.27%
74	G	T*	<0.35%	<0.35%	<0.35%	<0.35%	2.64%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	1	<0.35%	2.64%
189	G	A*	1.06%	0.92%	9.77%	0.37%	<0.35%	<0.35%	0.91%	0.39%	<0.35%	<0.35%	1	<0.35%	9.77%
408	A	T*	<0.35%	<0.35%	3.64%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	1	<0.35%	3.64%
1983	C	T*	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	1.76%	<0.35%	<0.35%	<0.35%	<0.35%	1	<0.35%	1.76%
6078	C	A*	0.52%	0.49%	0.82%	1.23%	0.44%	1.10%	2.99%	0.92%	0.54%	1.60%	2	0.44%	2.99%
8021	G	A*	0.37%	<0.35%	<0.35%	1.42%	<0.35%	1.87%	<0.35%	0.78%	0.39%	0.83%	1	<0.35%	1.87%
11090	C	A*	0.88%	0.67%	1.63%	1.12%	1.04%	1.65%	1.46%	1.62%	1.02%	1.24%	3	0.67%	1.65%
14274	C	A*	0.54%	1.6%	0.41%	<0.35%	<0.35%	<0.35%	0.92%	0.61%	1.18%	0.84%	1	<0.35%	1.60%
16092	C	T*	0.60%	0.53%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	<0.35%	0.54%	2.83%	1	<0.35%	2.83%
16093	C	T*	67.4%	43.6%	7.44%	73.0%	90.9%	81.6%	70.9%	63.8%	62.2%	60.1%	10	7.44%	90.9%
Total number of heterolasmic variants			1	2	6	1	4	4	4	2	1	3

^*Indicates the reference allele. Allele 1 frequencies equal or greater than 1.6% are shaded.