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. 2011 Jul 29;18(10):695–706. doi: 10.1038/cgt.2011.39

Table 1. Fluorescence and cellular uptake of formulated Dbait.

Molecules/method Dbait Chloroquine Fluorescencea MCC Cor MCC MCC Cor MCC
  (μg ml−1) (100 mg ml−1) × 106 μg−1ml−1 5 h 5 h 24 h 24 h
0 3 ND 3 ND
+ 0 3 ND ND ND
Electroporation 1.6 6.17 9 1 11 2
Dbait 1.6 6 3 0.4 3 0.5
Dbait/PEI11K 1.6 1.92 26 14 13 7
Dbait/bPEI25K 1.6 3.04 52 17 58 19
Dbait/PEI22K 1.6 3.32 54 16 43 13
Dbait/Superfect 1.6 6.41 220 34 204 32
Dbait/Superfect 1.6 + 6.41 218 34 ND ND
coDbait 1.6 3.47 10 3 ND ND
coDbait 1.6 + 3.47 21 6 ND ND
coDbait 16 3.47 66 19 64 18
coDbait 16 + 3.47 236 68 214 62
coDbait 32 3.47 145 42 ND ND
coDbait 32 + 3.47 390 112 ND ND

Abbreviations: Cor MCC, corrected cellular content FL2/fluorescence; MCC, mean cellular content FL2 value (>3 experiments); ND, not defined.

a

Fluorescence at FL2 value.