Table 3.
Adjusted* Associations Between Selected Respondent Characteristics and Increased Adapted Global Initiative for Asthma Score During Pregnancy by Prepregnancy Asthma Severity
| Factor | Prepregnancy Asthma Severity
|
||
|---|---|---|---|
| Intermittent [OR† (95% CI)] | Mild Persistent [OR† (95% CI)] | Moderate/Severe [OR† (95% CI)] | |
| Race | |||
| White | Reference | Reference | Reference |
| Black | 1.03 (0.81–1.32) | 0.69 (0.46–1.05) | 1.45 (0.86–2.43) |
| Hispanic | 0.96 (0.79–1.17) | 0.88 (0.63–1.22) | 0.85 (0.59–1.22) |
| Age (y) | |||
| 20–34 | Reference | Reference | Reference |
| Younger than 20 or 35 or older | 1.05 (0.83–1.34) | 0.96 (0.61–1.51) | 1.17 (0.65–2.11) |
| Atopy | |||
| No | Reference | Reference | Reference |
| Yes | 1.09 (0.91–1.32) | 0.83 (0.57–1.19) | 1.17 (0.74–1.86) |
| Prepregnancy BMI | |||
| Less than 26 kg/m2 | Reference | Reference | Reference |
| 26 kg/m2 or higher | 1.03 (0.88–1.21) | 1.31 (1.04–1.65) | 0.89 (0.70–1.13) |
| Parity | |||
| 0 | Reference | Reference | Reference |
| 1 or more | 1.03 (0.87–1.21) | 1.06 (0.83–1.35) | 1.08 (0.86–1.36) |
| Fetal sex | |||
| Male | Reference | Reference | Reference |
| Female | 0.91 (0.78–1.06) | 0.93 (0.72–1.19) | 0.81 (0.64–1.03) |
| Smoking history | |||
| Nonsmoker | Reference | Reference | Reference |
| 1st trimester only | 1.14 (0.88–1.47) | 0.93 (0.69–1.25) | 1.04 (0.73–1.48) |
| 1st and 3rd trimesters | 0.95 (0.71–1.26) | 1.29 (0.84–1.97) | 1.17 (0.68–2.02) |
| Gestational month | |||
| 2 | Reference | Reference | Reference |
| 3 | 0.98 (0.72–1.32) | 0.85 (0.57–1.27) | 1.33 (0.87–2.02) |
| 4 | 1.33 (0.99–1.78) | 0.99 (0.63–1.57) | 1.13 (0.73–1.74) |
| 5 | 1.29 (0.96–1.74) | 1.46 (0.93–2.29) | 0.85 (0.55–1.32) |
| 6 | 1.06 (0.78–1.44) | 0.57 (0.36–0.90) | 0.88 (0.56–1.39) |
| 7 | 1.31 (0.99–1.74) | 0.82 (0.53–1.27) | 1.10 (0.74–1.65) |
| 8 | 0.90 (0.65–1.24) | 0.76 (0.45–1.27) | 0.86 (0.51–1.43) |
| 9 | 1.13 (0.87–1.48) | 0.65 (0.45–0.94) | 1.05 (0.71–1.57) |
OR, odds ratio; CI, confidence interval; BMI, body mass index.
*
Transitional ordinal regression model of repeated measures adjusted for race, age, atopy, prepregnancy BMI, parity, fetal sex, smoking history, gestational month and season, and Adapted Global Initiative for Asthma score in prior gestational month.
†
Odds of Adapted Global Initiative for Asthma score being one level higher than if the respondent exhibited the referent characteristic.