Figure 4.

The significant results from the three-way interaction between the factors drug, valence, and memory during retrieval within the amygdala are shown. (a) Activation maps (threshold at p<0.001 uncorrected for displaying purposes), superimposed on a coronal slice of a standard T1 image, show a significant three-way interaction in the right amygdala. (b) To visualize this interaction further, parameter estimates are shown as provided by SPM. The bar graphs show the β-estimates of the specific contrast estimates of the recognition memory effect (ie, hits minus misses ±90% confidence interval). This demonstrates that the interaction arises because of an elevated recognition effect for the happy scenes in the duloxetine condition, which was also confirmed statistically by post-hoc analyses.