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. 2011 Jul 13;36(11):2276–2285. doi: 10.1038/npp.2011.115

Figure 4.

Figure 4

(a) Learning-induced changes in the mPFC–BLA pathway. Top: changes in the EFPs amplitude are expressed as a percentage of change from the baseline recording that was averaged for the two recording days. The EFPs amplitudes 24 h after FC (post FC) were significantly different between the three groups. Post hoc analysis showed a significant increase in EFPs amplitudes for the ‘FC only' and ‘FC+Extinction' groups compared with ‘Control' group, whose EFPs amplitudes did not significantly differ from the baseline levels. By contrast, extinction training was concomitant with a reduction in EFPs amplitudes in the ‘FC+Extinction' group compared with the ‘FC only' and ‘Control' groups post Ext1 and Ext3 (post Ext1, **p<0.005) and post Ext3, ***p<0.001). Bottom: representative traces of the main effects. (b) Learning-induced changes in the BLA–mPFC pathway. Top: FC was not associated with significant changes in EFPs amplitudes 24 h after conditioning. The amplitudes of EFPs were significantly different between the groups on post Ext1 (*p<0.05) and post Ext3 (**p<0.005). Extinction training was accompanied with a significant potentiation of EFPs in the ‘FC+Extinction' group compared with the ‘FC only' and ‘Control groups' (*p<0.005). Bottom: representative traces of the main effects.