Fig. 3.

(A) Histogram of interpulse intervals for three temporal patterns of DBS. Counts represent the number of interpulse intervals that fall within the bin range. (B) Behavioral response to three temporal patterns of DBS. All stimulations were physically identical except with respect to temporal patterning. Data represent 10 min during and 10 min immediately after stimulation; are normalized to 10 min immediately before; and are reported as mean ± SEM. **P < 0.01 vs. Fixed Frequency (FF); ^##P < 0.01 vs. Nonlinear2 (NL2). Adapted from ref. 46.