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. Author manuscript; available in PMC: 2011 Sep 20.

Published in final edited form as: Pediatr Infect Dis J. 2009 Mar;28(3):215–219. doi: 10.1097/INF.0b013e31818cc053

Table 2.

Comparative Pharmacokinetic Data for Lopinavir

Variable	Population
	Adult	Children	Infants 6wk-6m	Infants 2-6wk
	(Package Insert)	(Saez-Llorens^* n=12)	(Chadwick^# n=18)	(Current n=9)
LPV Dose	400mg	230mg/m²	300mg/m²	300mg/m²
*AUC (mcgh/mL)**	92.6	72.6	74.5	43.4
Cmin (mcg/mL)	5.5	3.4	2.0	1.4
Cmax (mcg/mL)	9.8	8.2	9.4	5.2

^#

Reference 6

^*

Reference 18