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. Author manuscript; available in PMC: 2012 Sep 2.
Published in final edited form as: Cell. 2011 Sep 2;146(5):826–840. doi: 10.1016/j.cell.2011.07.020

Figure 6. Reversibility of PTP oxidation in cancer cells following oncogene inhibition.

Figure 6

(A) Anti-phosphotyrosine immunoblot and (B) ROS levels of untransformed and Src Y527F cells treated with or without PP2, respectively. Data represent mean ± SEM (n=3; *** p<0.001, ANOVA with Bonferroni post-test). (C) Heat map showing effects of PP2 on levels of PTP oxidation in Src Y527F cells (n=2; 2 technical replicates each). * indicates PTPs with decreased oxidation following PP2 treatment.