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Ipsilateral ARNA in response to 12-HETE with or without 10−6 m AMG9810 or 10−4 m RP67580 perfused into the left renal pelvis of rats fed an NS diet (n = 5–7 in each group). A, ARNA activated by 10−11, 10−10, and 10−9 m 12-HETE given into the renal pelvis. B, ARNA induced by 10−10 m 12-HETE alone or with AMG9810 or RP67580. **, P < 0.01 vs. basal value; and ##, P < 0.01 vs. 12(s)-12-HETE alone group.
