Table 4.
Adjusted odds ratios for incident hypertension by slow wave sleep (SWS) quartile.
Adjusted characteristics | SWS Quartile 1 | SWS Quartile 2 | SWS Quartile 3 | SWS Quartile 4 | P value for trend |
---|---|---|---|---|---|
Age and BMI | 1.81 (1.18, 2.80) | 1.09 (0.70, 1.70) | 1.15 (0.74, 1.80) | 1.0 (reference) | 0.012 |
+race, study site | 1.83 (1.18, 2.85) | 1.14 (0.73, 1.78) | 1.18 (0.75, 1.85) | 1.0 | 0.012 |
+History of CVD | 1.84 (1.18, 2.87) | 1.14 (0.73, 1.79) | 1.17 (0.75, 1.84) | 1.0 | 0.012 |
+RDI | 1.86 (1.19, 2.91) | 1.14 (0.73, 1.80) | 1.18 (0.75, 1.85) | 1.0 | 0.011 |
+ total sleep duration, %sleep time, Pao2 <80%, overall arousals and sleep efficiency | 1.87 (1.18, 2.95) | 1.12 (0.71, 1.77) | 1.15 (0.73, 1.82) | 1.0 | 0.013 |
+alcohol use and current smoking | 1.82 (1.15, 2.88) | 1.11 (0.70, 1.75) | 1.15 (0.73, 1.82) | 1.0 | 0.019 |
BMI: body mass index CVD: cardiovascular disease RDI: respiratory disturbance index, number of apneas and hypopneas per hour of sleep, each associated with an oxygen desaturation of 4% or greater; Pao2: partial pressure of oxygen in arterial blood.
Alcohol use denotes ≥1 drink/week. Further categorization of alcoholic drinks per week 0, <1, 1-2, 3-5, 6-13, or 14+ did not significantly change results.