Figure 5. Predicted infection intensity at different ages in a community having continuing Schistosoma transmission during control.

The upper panel indicates the life path experience with infection intensity (annual mean egg output per specimen) without therapy (No Rx), with single-dose annual therapy (1Rx), with or double-dose annual therapy (2 Rx), and 80% annual adherence in a community-based treatment program when there is continuing transmission of Schistosoma during the control intervention. The lower panel indicates the expected lifetime impact of the same regimens in a program treating school-age (5–15 yr) children only.