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. 2011 Sep 20;5(9):e1321. doi: 10.1371/journal.pntd.0001321

Table 3. Observed reductions in Schistosoma infection intensity in selected field studies.

Study [citation] Country Location Study Size Diagnosed with Local Pre-treatment Prevalence Two Dose Interval Follow up interval One Dose-Any Intensity One Dose-Light Infections One Dose-Heavy Infections Two Doses-Any Intensity Two Doses-Light Infections Two Doses-Heavy Infections
Reported reduction in Schistosoma mansoni infection intensity
Barakat, 2010s [12] Egypt 588 1 stool, KK 44% 4 weeks 4 weeks 71% 34% 87% 74% 34% 89%
Utzinger, 2000s [21] Cote d'Ivoire 253 4 stools KK 77% 5 weeks (60 mg/40 mg) 4 weeks 80% 89%
Black, 2009a [13] Kenya 178 3 stools KK 83% 6 weeks 4–6 weeks 83% (62–91%)
Picquet, 1998c [18] Senegal 113 1 stool, KK 87% 6 weeks 4 weeks 71% 30% 88% 88% 56% 96%
Kabatereine 2003c [14] Uganda 617 3 stools KK 92% 6 weeks 6 weeks 98% 99.6%
Reported reduction in S. haematobium infection intensity
Midzi, 2008s [16] Zimbabwe 675 3 urines, filtration 51% 6 weeks 4 months 94%
Mduluza, 2001s [15] Zimbabwe 595 3 urines, filtration 52% 8 weeks 8 weeks 96% 92%
Tchuem-Tchuente, 2004s [20] Cameroon 515 2 urines, filtration 42% 3 weeks 6 weeks 98% 98% 99% 99% 98% 99.7%
N'goran, 2003s [17] Cote d'Ivoire 354 4 urines, filtration 77% 4 weeks 3 weeks 97%
Sacko, 2009s - [19] Selingue Mali 256 3 urines, filtration 87% 2 weeks 3 months 99% 99%
Sacko, 2009s - [19] Koulikoro Mali 300 3 urines, filtration 95% 2 weeks 3 months 98% 99%
s

Study based on school age participants only;

a

Study based on adults only;

c

Community-based study.