Figure 1. Schematic representation of ARTS domains.
The domain structure of ARTS/Sept4_12 is based on its alignment with the sequence of the longer isoform Sep4_i1. The domains are: N-terminal domain, NTD, residues 1–100; polybasic linker, PB, residues 101–124; truncated GTPase domain, t-GTPase, residues 125–247; and the C-terminal domain, CTD, residues 248–274. The P-loop motif is also annotated, residues 132–139.