Skip to main content
. 2011 Sep 20;6(9):e24480. doi: 10.1371/journal.pone.0024480

Table 1. Spearman's correlations using alternative recombination rate datasets.

Variable Statistic Overall genic Weighted mean Base pair median Interval mean Interval median Mean smoothed1 Median smoothed1 Mean smoothed2 Median smoothed2
X Y Z
K i GC RRSA ρ −0.081 −0.081 −0.081 −0.081 −0.081 −0.089 −0.083 −0.092 −0.081
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001
RRM ρ −0.08 −0.079 −0.079 −0.079 −0.079 −0.085 −0.079 −0.088 −0.077
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001
RRF ρ −0.08 −0.08 −0.08 −0.08 −0.08 −0.081 −0.079 −0.083 −0.078
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001
RT RRSA ρ −0.08 −0.08 −0.081 −0.08 −0.08 −0.086 −0.079 −0.087 −0.077
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001
RRM ρ −0.081 −0.081 −0.081 −0.081 −0.081 −0.089 −0.082 −0.09 −0.082
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001
RRF ρ −0.078 −0.078 −0.079 −0.078 −0.079 −0.076 −0.078 −0.076 −0.077
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001
RRSA - ρ 0.045 0.041 0.038 0.045 0.043 0.095 0.084 0.1 0.088
P 0.007 0.015 0.023 0.007 0.01 1.24×10−8 5.14×10−7 2.39×10−9 1.67×10−7
RRM - ρ 0.015 0.01 0.006 0.013 0.009 0.057 0.054 0.058 0.057
P 0.379 0.544 0.73 0.454 0.574 0.001 0.001 0.001 0.001
RRF - ρ 0.044 0.041 0.039 0.044 0.043 0.084 0.071 0.092 0.08
P 0.009 0.015 0.02 0.008 0.01 5.22×10−7 2.62×10−5 4.25×10−8 1.81×10−6
RRSA GC ρ 0.051 0.047 0.044 0.05 0.049 0.104 0.088 0.111 0.09
P 0.002 0.003 0.003 0.001 0.005 0.001 0.001 0.001 0.001
RRM GC ρ 0.021 0.016 0.013 0.019 0.016 0.067 0.055 0.07 0.056
P 0.114 0.178 0.234 0.137 0.157 0.001 0.003 0.001 0.001
RRF GC ρ 0.047 0.044 0.043 0.047 0.046 0.087 0.071 0.096 0.08
P 0.004 0.005 0.005 0.002 0.004 0.001 0.001 0.001 0.001
RRSA RT ρ 0.042 0.039 0.037 0.043 0.041 0.1 0.082 0.105 0.084
P 0.008 0.01 0.012 0.005 0.014 0.001 0.001 0.001 0.001
RRM RT ρ 0.017 0.012 0.01 0.015 0.012 0.068 0.055 0.07 0.058
P 0.162 0.209 0.3 0.197 0.213 0.001 0.001 0.001 0.001
RRF RT ρ 0.038 0.035 0.035 0.039 0.038 0.08 0.067 0.088 0.076
P 0.013 0.015 0.022 0.013 0.015 0.001 0.001 0.001 0.001
GC RT RRSA ρ 0.296 0.295 0.294 0.295 0.295 0.29 0.294 0.289 0.294
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001
RRM ρ 0.292 0.291 0.29 0.292 0.291 0.283 0.293 0.278 0.293
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001
RRF ρ 0.296 0.296 0.295 0.296 0.296 0.295 0.293 0.296 0.293
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001
RRSA - ρ 0.067 0.068 0.077 0.067 0.07 0.102 0.048 0.126 0.031
P 6.44×10−5 4.80×10−5 4.51×10−6 6.46×10−5 2.76×10−5 1.07×10−9 0.004 4.45×10−14 0.064
RRM - ρ 0.078 0.078 0.085 0.078 0.081 0.111 0.01 0.144 −0.016
P 3.33×10−6 3.19×10−6 3.85×10−7 3.79×10−6 1.39×10−6 3.39×10−11 0.539 0 0.343
RRF - ρ 0.038 0.037 0.048 0.035 0.041 0.027 0.005 0.044 −0.007
P 0.025 0.026 0.005 0.036 0.015 0.104 0.753 0.008 0.692
RRSA RT ρ 0.081 0.08 0.083 0.079 0.08 0.092 0.057 0.116 0.046
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.005
RRM RT ρ 0.074 0.073 0.074 0.073 0.074 0.079 0.008 0.109 −0.02
P 0.001 0.001 0.001 0.001 0.001 0.001 0.318 0.001 0.116
RRF RT ρ 0.063 0.061 0.064 0.059 0.061 0.048 0.021 0.064 0.011
P 0.001 0.001 0.001 0.001 0.001 0.007 0.104 0.001 0.252
RT RRSA - ρ −0.034 −0.027 −0.009 −0.03 −0.022 0.048 −0.024 0.051 −0.045
P 0.041 0.102 0.578 0.074 0.188 0.005 0.148 0.002 0.008
RRM - ρ 0.025 0.028 0.049 0.026 0.034 0.122 0.01 0.138 0.01
P 0.135 0.095 0.004 0.122 0.041 2.6×10−13 0.56 1.2×10−16 0.547
RRF - ρ −0.076 −0.07 −0.046 −0.073 −0.061 −0.062 −0.051 −0.056 −0.059
P 6.34×10−6 3.19×10−5 0.006 1.37×10−5 0 0 0.003 0.001 0
RRSA GC ρ −0.056 −0.05 −0.033 −0.052 −0.045 0.019 −0.04 0.015 −0.056
P 0.001 0.003 0.02 0.001 0.005 0.14 0.009 0.189 0.001
RRM GC ρ 0.002 0.005 0.025 0.003 0.011 0.095 0.007 0.102 0.015
P 0.443 0.376 0.067 0.423 0.255 0.001 0.349 0.001 0.171
RRF GC ρ −0.091 −0.084 −0.063 −0.087 −0.076 −0.073 −0.054 −0.072 −0.06
P 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001 0.001

Spearman's correlations at the genic level for each alternative method used to curate genic recombination rate data where: Z = the controlling variable used in partial Spearman's correlations between variables X and Y; K i = intronic substitution rate between mouse and rat; RT = median replication time for each gene; GC = repeat-masked intronic G+C content for each gene; RRSA, RRM and RRF = sex-averaged, male and female genic recombination rates respectively.