Figure 4. Stat5-binding short peptides inhibit the in vitro growth of Ba/F3 and TF-1 cells.

Ba/F3 (A, C) or TF-1 (B) cells were retrovirally transduced with the indicated peptides. GFP⁺ transduced cells were FACS-sorted, cultured, and Trypan Blue-resistant live cells enumerated. (C) Growth inhibition of Ba/F3 cells by shorter peptides derived from peptide b. Inhibitory ability was defined as the ratio of (relative cell number in empty vector-transduced cells – relative cell number in peptide-transduced cells) to (relative cell number in empty vector-transduced cells –relative cell number in PLC-β3-CT transduced cells).