Fig. 4.
Effect of oral administration of jellyfish collagen extracts on Ig level in serum. Female 6-week-old BALB/c mice (6 animals per group) were orally administered 10 mg·kg body weight−1·day−1 of jellyfish collagen extracts or 10 mM NaPB as vehicle control for 28 days. The serum was obtained by drawing blood from the eye socket on days 7 (a) and day 28 (b). IgA, IgG, and IgM concentrations in the serum were measured using ELISA. Solid bars and open bars show the Ig levels in the serum of mice administered the vehicle control (VC) and jellyfish collagen extracts (JC), respectively. The results are presented as mean ± SD (n = 6). Asterisks indicate that the data are significantly different as compared to control data. *p < 0.05