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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Cancer Gene Ther. 2011 Sep 2;18(10):744–750. doi: 10.1038/cgt.2011.47

Figure 3. In vivo oncolytic activity of selected adenoviruses against human breast and ovarian cancer xenografts.

Figure 3

Tumors were implanted subcutaneously in nude mice. Once tumors formed, they were treated a single time by intratumoral injection with 3×1010 viral particles of the indicated viruses and tumor sizes were measured over time. Average tumor size for the group is plotted. Tumor size line terminate when an animal must be sacrificed due to tumor size, tumor hemorrhage, or for other care issues to avoid the artifactual appearance that tumor size for the group have reduced when one animal is removed. A) MDA-MB-468 human breast carcinoma tumors (N = 10 mice per group). B) SKOV3 human ovarian carcinoma tumors (N = 8 mice per group).