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. Author manuscript; available in PMC: 2012 Apr 1.
Published in final edited form as: Cancer Gene Ther. 2011 Sep 2;18(10):744–750. doi: 10.1038/cgt.2011.47

Figure 4. Effects of adenoviruses on hamster cancer cells in vitro and in vivo.

Figure 4

One week cell viability of several hamster cell lines was monitored by trypan blue uptake upon infection with adenovirus (A-D). CHO-CD46 and CHO-CAR cells were derived by transient transfection of CHO cells with CD46 or CAR cellular receptor expression plasmids. E) HaK hamster kidney cell tumor growth was monitored in Syrian Hamsters following intratumoral injection of 3×1010 viral particles in immunocompetent Syrian Hamsters. Average tumor size for the group is plotted as in Figure 3. N = 6 hamsters per group.