Fig. 2.
Effect of pretreatment with the μ opioid receptor antagonist CTOP on EA-produced inhibition of hyperalgesia and allodynia in a paclitaxel-induced peripheral neuropathy rat model (n=7 per group). EA plus vehicle significantly decreased mechanical response frequency compared to sham EA plus vehicle. CTOP pretreatment blocked EA-produced inhibition of hyperalgesia and allodynia. * P<0.05 and ** P<0.01 between vehicle + sham (△) and vehicle + 10 Hz EA (▲); # P<0.05 and ## P<0.01 between CTOP + 10 Hz EA (●) vs vehicle + 10 Hz EA (▲).